As a handloader, I went with 7mm magnum when I wanted a big gun. I like the 7mm ballistic coefficients. All I had at the time was a .257 Roberts and I was thinkin' I'd get to go elk hunting, never happened. Bummer. I used it on some rocky mountain mulies and west Texas whitetail, but no elk. I was really thinkin' .280, but I reasoned that I could always down load the mag to .280 performance if that's what I wanted. I never did, though. I later got a .308, so I wound up with a .30 caliber after all.
I don't think one will kill anything any deader than the other. I was looking at the numbers with the 7. It'll reach as far as I wanna shoot and shoot a little flatter and deliver a bit more energy on target at any range. In retrospect, though, older and wiser, which ever one floats your boat. I got the 7 in a Savage 110, 2" longer barrel and a different bolt face, but otherwise the same gun as I could have gotten in .30-06. It's a good shootin' gun even though, now, I really have little use for it back here in the woods on whitetail. I don't hunt out west anymore, but may again someday, never know. Around here, I've really been getting into my CVA Wolf front stuffer. It's kinda the polar opposite, 385 grains of 50 caliber bullet loping along at about 1500 fps. It gits 'er dun, though.
I could see POSSIBLY getting a 75 yard shot out here. If I need a centerfire rifle, my old tried and true .257 is really enough, or my .308. Both are Remingtons.