22 mag vs 17 for 100yd rodent control

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100 yards isn't a problem for either. If you shoot small varmints further out then I would go with the .17. If you shoot bigger varmints I would go with the 22 mag. Savage, Marlin and CZ all make decent or better rifles for these rounds.
 
I'd say at 100 yards there's just not a lot of difference accuracy wise, I think the .17 breaks up in just about anything it hits with the .22 mag tends to penetrate farther.
The accuracy difference can be huge! A great many budget priced .17's will shoot well under MOA. Savages and CZ's quite often shoot half-MOA. With the .22Mag, you're lucky to get much under 2MOA.

The 20gr XTP penetrates very well and is quite effective, even on coyotes.
 
My friend hunts coyotes near his property with his father in law. His father in law uses a Savage 17HMR and hasnt had any problems with it taking down coyotes. Just like any other caliber you have to buy the correct bullet for the game.
 
For slaughtering farm animals a .22 mag works pretty good point blank. But for most rim fire shooting the .17 is top dog.
 
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