I think your charge of H110 is too low, that's why the extreme spread is so high. I also wouldn't use it with a plain based bullet. Really need a gas check and max loads for H110 to be applicable.
Unique is a wonderful powder if it yields the desired velocity. I use more of it than anything else.
No it won't, not even close. Even out of a 3" barrel, H110 is going to yield significantly higher velocities. By that I mean 200-300fps.