OK, I finally listened to that part of the broadcast, and found it rather...curious.
They were talking about both penetration and expansion, saying that there is really no difference between these calibers, and claiming that this is somehow an impressive result achieved by premium ammunition. All I can say is that there is no magical technology that can give .380 ACP the same wounding potential as 9mm, which has significantly greater energy and momentum to work with. The only way to completely equalize them that I can think of would be to make the 9mm load anemic, bringing it down to .380 ACP's performance level--that would indeed be easy to do.
While I don't have terminal ballistics performance data for Critical Defense, the rounds are loaded practically the same as those of Hornady's XTP line, and the latter's .380 ACP load has 11.4" penetration and .54" expansion. If Hornady's 9mm load gets practically identical results, as said on the Podcast, then it's either a weak or inefficient 9mm load. Perhaps it dumps its additional energy into a temporary stretch cavity and thereby wastes it, but that would not be identical performance (hits harder and potentially causes more pain). Other 9mm loads I've seen that have similar expansion generally penetrate about 4" more deeply, which to me is a significant difference. Maybe Hornady's own 147 grain 9mm load would have similarly superior penetration, which would mean that the comparison is apples-to-oranges. It's also possible that the 9mm round expands immediately and thereby crushes more tissue overall, but the commentators failed to realize this, so captivated were they by the magic of .380 ACP performing exactly like 9mm (or rather 9mm performing down to .380 ACP's level).
My doubts about the weird .410 PDX1 load aside, it is possible to compensate for certain shortcomings of specific platforms, as I said earlier, but you cannot optimize both a weaker caliber and a more powerful caliber, and end up with the same result. How? One of them must be suboptimal, then, or have higher performance in an area that is not being considered.
.380 ACP has always penetrated more than enough by most standards if you used FMJ rounds--about 21"-22" would be typical. In the past, manufacturers have tried to optimize the use of the caliber's energy by using JHP bullets that expand, just like they did with 9mm and other calibers, but the bullets often did not expand, resulting in the same performance as FMJ. Now that they've managed to solve the problem, the bullets are getting less than 12" of penetration and about 50% expansion. For those who are focused on successful expansion and reduced risk of overpenetration, as many people are, this is superior performance, but in terms of energy it's nothing that .380 ACP wasn't theoretically capable of before, and in the big picture of terminal performance, it's not necessarily superior, either.
9mm still has greater energy and potential for wounding--nobody has made .380 ACP its equal all of a sudden. Nothing has changed in that regard--it's all about how you optimize the loads, and something is definitely off with this comparison (either that or Hornady's product line). I know of 9mm loads with terminal ballistics that .380 ACP physically cannot match, and that's why many people still use 9mm instead of abandoning it altogether.