ShooterMcGavin:
OK, one or possibly two handguns.
Some very well-informed folks on this board have given you a lot of good information, but I don't see a lot of it as applicable to a one/two handgun situation.
Now that we have narrowed down the "what" you wanna lock up, we need to know what sort of access (quick & loaded vs slow & unloaded), your circumstances (small kids, klepto room mates, etc.), purposes (keep from determined burglars, keep from kids, fireproof, etc.) and such.
Let me give you my circumstances, desires, and my solutions.
1. Several long guns & hand guns
2. Small children in the house
3. Small house, no room for any long gun safe
4. I want quick access to some loaded handguns for home defense and to store my carry handguns
Quick Access
For quick access to my HD & carry handguns, I have two of these:
http://www.walmart.com/catalog/product.do?product_id=2221464
$60.00 delivered to your local Wally World.
Lots of folks produce something similar with different features at different price points.
Essentially, a quick access locking box that has a programmable key pad and a key lock entry in case the batteries go bad or you forget your combo. I bought my first one ~3 years ago, stoked it with top-end lithium AA batts and it still works on the original batteries. It will hold two handguns comfortably, four in a pinch. I can open it in the dark. All in all, it has worked well for me.
What it is not is burglar proof. It can be bolted down, but a crow bar will separate it from your anchor. Also, it is not fire proof.
It keeps my loaded & ready to go guns from my toddlers and prying visitors. I do not expect a determined thief to be stymied if he has a crow bar.
If the electronic keypad gives you the willies, similar QA boxes with Simplex locks (the maker to go with for push-button mechanical locks) can be had:
http://www.ftknox.com/pistolboxes/
This one goes for ~$190.
I would rate it as a better quality box than the DAC above. But, it was a budget-buster when my first born was on the way. The DAC box was the best we could do at the time.
NOT SO QUICK ACCESS
The best we could do for the long guns was to replace the door knob on a closet with a dead bolt. Again, a burglar with time & a crow bar can get at the weapons. But, they are out of my kids' reach and out of the prying eyes of visitors. Unloaded handguns also reside here.
My ammo will go in padlocked metal boxes, as soon as I refinish the two metal footlockers I scavenged the other day.
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Any serious safe that will give a burglar fits will be a costly proposition.
Good luck.