I never trust rimfire in an autoloader for anything serious. If you're just lookin' for a plinker, it's dirt cheap, but fairly reliable and REALLY accurate for a tiny gun and you can buy one with pocket change, the Phoenix HP22. I have one and like it for plinking, dispatching vermin. It's the only pocket gun I've ever fired with the accuracy to shoot small game at longish ranges. It's totally amazing to me, but that little gun will but 10 rounds of CCI stinger into 3" at 25 yards.
Since I consider .22 way to short on horsepower for anything serious like self defense, this little gun is as good to me as any Beretta which might have less accuracy. I have the spare 5" barrel/mag with finger extension, too, and with cheap federal, it'll shoot 2" 25 yard groups. The extra sight radius is why, I'm convinced. It defies logic, I know, but it's true.
If you want something 100 percent reliable in rimfire, consider an NAA mini revolver, maybe a mini master. If a round fails to fire, there's another one ready to rotate into position. Depending on brand of ammo, I get quite a few failures to fire with .22 in several guns. Guns with a wider firing pin helps, but they're notorious for priming flaws in the rim. And, no rimmed cartridge with heal/external lubricated bullet is fit for autoloaders IMHO. The HP.22 is amazingly reliable at feeding 'em, but no autoloader is immune to problems with such a round. Give me a good revolver for rimfires every time.