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Well see, your subject says Favorite Pistol Ctg, but then in the post you said centerfire only. So, I can't say .22 Long Rifle.
That is by far the most fun and versatile cartridge around.
But, to play by the rules, I'd go with the 9x19 in autos, and the .38 Spl in realguns.... whooops, wheelguns. Sorry, them's my roots showin'.
45 ACP. Time proven abilities on paper and more serious targets. Main limitation I see is reduced capacity and that isn't a liability if you hit what you aim at. If the 45 ACP disappeared, I'd go with either 38 Super, 9x23 or 10mm.
I don't handgun hunt. If I did, I would probably lean towards either a 41 Magnum or a 44 Magnum.
Mine used to be .357 Magnum but, I would have to say .45 Colt now... I like the larger bullet with less felt recoil out of my Super Redhawk... Either would /have served in many capacities
I bought a Super Redhawk in .454 Casull/.45 Colt due to it's versatility. I handgun hunt a lot. The .454 is not just a powerhouse, it shoots very flat, so I don't have to compensate much within the distance I am able to see and shoot. I have taken elk, wild boar, deer and other critters. I have taken rabbits with downloaded .45 Colt wadcutters, which leave a nice hole, but don't blow up the rabbit. It's fairly cheap to shoot if you handload, which I do not just to save money, but because I can't find all the loadings I want.
With the proper ammunition selection, the 9mm, .357Sig, .40 S&W or .45 ACP can do the job with good efficiency. There can be no argument about the capability of the .357 Mag to perform admirably.
I just like the ability of the 10mm to combine the best desires of capacity and power into a package, that for me, is not difficult to conceal or control.
As I said, a personal coice, not a flame or poke in the eye to anyone else's choice.
Hands down .357mag. For defensive use I'd be more likely to use .38 or .38+P and I use .38 more in practice since its so cheap but I LOVE the magnums. Nothing puts the same kind of smile on my face.
For autos (and runner up overall) I like 9mm for all the reasons others have said. Cheap practice ammo yet with premium ammo it is every bit as effective as just about any other service caliber.
If it was financially independent it would be a toss up between 9mm and .45acp for autos.
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