I had the luxury of shooting two Medusa revolvers a few years back.
One was a genuine Phillips & Rodgers Model 47 and the other was a S&W Model 27 that had been retrofitted with a Medusa cylinder.
It was an interesting demonstration. Yes they did chamber, fire and extract .380, .38S&W, .38 Short Colt, .38 Long Colt, 9mm Luger, 38 Largo, .38 Super, 9x23mm, .38 Special, .357 Magnum and even 9mm Win Mag.
(and perhaps even a few more obscure ones that I can't remember)
Point of aim varied but accuracy seemed acceptable.
But I have never seen such a conglomeration of bulged, blackened and deformed cartridge cases in my life.
HELLO!!!
There is a reason that they make separate loading dies for those calibers.
THEY AIN'T ALL THE SAME!
Perhaps in a SHTF/EOTWAWKI scenario it might be good for those Mad-Max types roaming the countryside scrounging ammunition but I prefer that my ammunition properly fit my firearms.
It amazes me that people will in one breath say something like, "You better not fire .38 Specials in that rechambered WWII .38-200 S&W M&P. The cases will split and you'll blow your eye out." But in the next breath they'll remark, "Oh the Medusa is so COOL. You can shoot ANYTHING in it."
But then, perhaps it's just me.
Maybe I have a warped sense of safety or something.