I've shot the LCR and Smith 442 back to back at a rental range and preferred the Smith. It just felt better - to me - to shoot, and I shot it more accurately. I later shot the S&W Bodyguard (they didn't have it when I'd shot the LCR) and the 442 back to back, and again preferred the 442 - the LCR was checked out when I was there for this session. Of course, YMMV.
Personally I would NOT have a laser sight that I had to turn on with a separate finger movement (as on the S&W Bodyguard) if I could have the Crimson Trace grip-activated switch. So if I could only choose between the LCR and Bodyguard I'd pick the LCR just for the laser sight switch. But given the option of a 442 (which I just ordered one of) I'd pick that one over either of the others.