They are built with the idea of carrying locked and loaded in mind. You are not going to hurt it by having it in
condition 1 or by storing it with the striker spring compressed.
They are designed to run thousands upon thousands of rounds through them. It's the same as storing your mags fully loaded. The spring wears out from cycling not constant compression.
Here's an explaination in case you aren't familiar with the conditions.
Condition One: Ready To Rock
In Condition One, the pistol has a cartridge in the chamber and a fall magazine inserted into the magazine well. This state of readiness occurs just prior to firing the gun.
In Condition One, a Glock handgun is brought into action simply by being brought on target. When placed on the trigger, the shooter's finger disengages the safety lever located in the middle of the trigger.
In Condition One, 1911 pistols are in a mechanical state commonly called "cocked and locked." In this mode, the hammer is back and the thumb safety is up and in a locked or "safe" no-fire position. The magazine is full and in place.
To bring into action, the 1911 is brought on target, the thumb safety depressed into fire mode and the trigger is accessed. The 1911 also requires that the grip safety located at the back of the frame be depressed in order to fire the pistol.
In Condition One, a firearm is in its fullest state of readiness. The operator is simply required to draw or present the pistol to the threat and apply the mechanics necessary to make the pistol fire. Condition One would be a correct choice when it is necessary to carry the pistol in a state of readiness for potential imminent use.
The rest of the conditions can be found here:
http://findarticles.com/p/articles/mi_m0BQY/is_8_46/ai_63772593/