I really like my S&W M22A but I suspect I'm in the minority. Mine had to go back to S&W for repair, great service, they paid shipping both ways so I've no complaints. While the gun takes down for cleaning very easy, it practically takes three hands to reassemble and the root of the problem I had is the poor design of the method the back of the upper engages the frame -- this losened up causing mis-fires from very weak primer hits.
Really like our Buckmark, but its as bad to take down for cleaning as the Rugers are since you need two different sized hex head wrenches, but its a great shooter. Also not the best choice if you plan on mounting an optic.
Hard to go wrong with a Ruger.
The Beretta Neos is great if you can get over its weird looks and the fact the safety rotates the "wrong" way. Its one of the best if you plan on mounting an optic or red dot sight. Another plus is CDNN has had spare Neos mags on sale for $10 each for the past few months. Takedown and reassemble of the Neos is a snap, but it does leave spring under pressure when disassembled so you need to be careful. If you are a lefty, the Neos is the only one with an ambi safety.
IF you are like me, draw straws, they are so much fun once you get back into shooting .22s that its easy to buy them all eventually.
--wally.