H110 is the same powder as 296, I hope that little tidbit might find some info.
I used to use a copious quantity of H110 under a 300 grain Meister cast bulet in a S&W Mountain Gun I had but I can't find the notes. As I recall it was a compressed charge, and I know for sure I wrecked the gun with it. Shot it loose in a hurry, less than 3500 rounds and it rattled like a GI 1911. The front sight pins used to break regularly too, it would fly off into wherever things go that you never find again....
300's in a 44 have always shot well for me too.