A typical weekly Wednesday range visit will include 48 to 96 shots with one or more of the cap and ball revolvers, or 50 to a hundred rounds of 45 Colt in one of the conversions, black powder or Trail Boss or a combination of both. To me one shot or 50 shots with black and the guns has to be cleaned.
The Colts, ROA’s and R&S will all shoot the 48 rounds with no problem. The Armi San Marco NMA will require a cylinder dismount after 12 to 18 rounds.
I also have two single shot pistols but they get a wet patch after two or three shots.
This is with Graffs house brand of 3f, my primary concern is more bang for my buck.
Course, this is casual recreation shooting at 12 yards, and no ones keeping score.
On the point of accuracy, off hand shooting, at my level I seriously doubt if the powder brand would make a difference.
Once the wood is pulled and the piece goes under the hot water tap with some Dawn, a tooth or bore brush, powder fouling is academic. High pressure air blow down and a liberal application of Balllistiol and done. Tops 10 minutes per piece.
Just my three cents worth.