In the specific case of a Triple Lock, it would have to be pretty far gone before I'd be willing to take a hacksaw to it. Honestly, if I really had to have a chopped Triple Lock, I'd keep an eye out for a basket case and then send it to a reputable revolversmith.
Now, I have attacked old revolvers with hacksaws and Dremel tools, but they were rusty examples of police trade-in Model 10s and the like, so I don't feel like I painted over the Mona Lisa. The end result, though, never did match the picture I'd had in my head. For that reason alone, if I had it to do over I wouldn't.