Eh, I'm a little on the conservative side. 200 rounds of quality JHPs after a hundred rounds of ball, through every magazine I have for the pistol has typically proven sufficient.
Unless it's a (1) a used pistol, especially if I don't know the previous owner(s) or (2) a 1911 -- I'm careful about deciding when these critters are reliable and may go another 200 rounds beyond. Not that I don't believe a 1911 can be as reliable as any other modern handgun, but I'm superstitious that way. Have a sweet Colt's 100 Years of Service LW Commander that suddenly became finicky after around 300 rounds without a malfunction and it took a bit of investigation 'til I got it cleared up...
Although, if I was forced to carry a handgun I'd just bought off the shelf without firing any rounds through it, I'd probably not worry too much if it were almost any new SIG, Glock, Beretta or CZ (I might feel a little better if I had a chance to clean and lubricate it first, sometimes the factory grease turns into sludge).