There are some knowledgeable folks who say that it isn't the power level of the 125 JHPs so much as the hazards of shooting jacketed bullets through a forcing cone that has built up lead in it. The portion of the barrel protruding into the cylinder window in the 19 is pretty thin-walled, and can't take a whole lot of abuse. Pressures spiked by firing a hard bullet into a wad of lead can cause the forcing cone to split, or so goes the theory.
Brian Pierce did a write-up some years ago where he fired 5000 full-power magnum loads through the gun. IIRC, half were lead and half were jacketed. He said the gun had loosened up a bit at the end of it, but was actually a bit more accurate than it had been when new. So I don't think we have to be super careful with the thing.
Having said that, no, it's not an N-frame. I load mine down a hair, for the most part. 158 SWC at 1200 FPS should be pretty easy on the gun, and of course, 148 lead wadcutters at 800 FPS will allow the gun to live essentially forever.
Have fun!