Everything in life is a compromise of some sort. Handgun cartridges are no exception.
To the .460 fan... I gotta say 'meh'. I've shot a .460, will probably shoot another someday. I'm not going to get into the very real recoil/self-damage issue, instead skipping straight to the fact that the smallest .460 revolver is like a 2x scale chief's special. It's comically huge and a five shot. You can't realistically concealed carry that, at least not around here. My reaction to shooting a .460es (X-frame snubby) was to run out and buy a .454 Ruger Alaskan.
To the don't confuse big with versatile I say don't confuse size with power. If a single cartridge can be loaded to hunt rabbits and elk, and do a fair job at both, that's versatile regardless of the size.
To the premise of .44 as the most versatile, I'm kinda on board, with some ifs and buts. The main but is that the title actually extends to large-bore cartridges in general. .44 mag, .45 colt, I guess even .41 though I don't have any experience there. The chief if is that it mainly applies to hand loaders. These guns all tend to be far more accurate than the people shooting them, and they can be loaded mild or wild as needed.
I wouldn't trade my .454 Alaskan for a .44 version. The size and weight are very similar (the .44 is an ounce heavier, the length is identical) and my .454 can run from mouse belch cowboy loads up to full house .454 that are nothing to sneeze at...I've read reviews claiming 240gr bullets run ~1600fps out of that 2.5" barrel). I find it to be surprisingly accurate though it takes a fair amount of self control to shoot more than a few cylinders of full power loads well. I wouldn't feel under or over gunned facing down anything from a bullfrog to a ... I don't know, something big.
However...how much actual loss is there in going to a .357? Enough to really make a fuss over? I certainly don't know enough to claim that my hand cannon is really a better choice than a .357. It was just my choice. Life is too short for fanboiism.