Standard autopistol rounds such as the 9mm, .40, and .45 ACP are very much on the LOW side for the intended purpose of "stopping" an adult male human. The 10mm with REAL 10mm loads has the capacity to add something useful to the equation, however, the load you quoted it by no means a "10mm" level load...as another poster stated, it's a .45 ACP equivalent load.
Underwood makes THE BEST 10mm ammo available today at any price. For self-defense you simply do not need a 200 grain 10mm bullet, but Underwood makes 10mm loads in every conceivable weight.
I would suggest the 155-165 grain weight delivering 750-800 lb-ft of KE...which is what the 10mm was originally developed to do.
If all you want is .45 ACP power, then you didn't need the spend your hard earned money on a 10mm.