Comfort is relative. There is a lot to your mindset, and being willing to accept the weight and bulk. You can take a guy who turned 21 precisely 60 days ago, and just got his permit in the mail, shivering with excitement that he is FINALLY allowed to carry, and hang a Desert Eagle under his left arm, and he will SWEAR that he can't feel it. On the other hand, if you take a petite anti female, (oh yeah, I'm playing the gender stereotype card,) and have her try to conceal a Keltec....anything, in her pocket, in her purse, in the waistband, wherever, she will say it feels like an iron tumor. We have the luxury of having a lot of guns and sizes to choose from. Ask yourselves, if technology only permitted full-size, all-steel guns, would you not carry? Or would you find a way to live with it?
I use a Crossbreed Supertuck and a Galco paddle magazine/flashlight holder on the opposite side, 100+ degree summers. Shorts and a t-shirt, no big deal. I can carry anything I want to, this is what I choose, because this is what I shoot best.