The .223 as a HD rifle is advocated largely by advertisments and mall ninjas.
Well nobody is paying me money, so I guess that makes me a mall ninja? A light recoiling rifle with a large magazine makes a very nice home defense tool. Here is a test you can do - take some silhouette targets, a shot timer, and a few novice shooters out to the range. Have them do some home defense scenarios with a handgun, 12ga shotgun (loaded with defensive ammo) and a small caliber centerfire rifle like an AR, AK or Mini-14. See which weapons show both the best times and best hits.
For any non armored invader conventional wisdom shows the shotgun to be the prevailing HD tool.
Well, if we are going to make choices based on what the prevailing home defense tool is, we should be discussing whether speed dial, rotary dial, or touch tone is the best for home defense.
Frankly I think the idea of using a rifle firing a rifle cartridge inside of your home will generally result in shots through walls and unintended targets getting hit.
Yes, it is a popular myth even in this thread where people still repeat it after being pointed to several sites where they could see for themselves what the effects of .223, handgun and shotgun rounds are on various intermediate barriers.
About the only myth with similar popularity is the one that you can feed your rifle any old .223 and it will be instantly stopped by a single sheet of drywall but still stop an attacker - and this is also simply not true. Wolf ammo for example will penetrate like nobody's business - as will the Federal TBBC soft points, and about 25% of the time military ball ammo as well.
At the end of the day, anything that will stop a 200lb mammal is going to zip right through multiple layers of drywall and still present a lethal threat. However, some rounds will be less lethal than others and a platform that allows you to put the rounds on target will negate a lot of the problem of worrying about misses.