I've fired a Heritage and it is a nice shooting revolver. I have a single six and like it much better. The Heritage is about half the cost of the Ruger. The Ruger is heads and shoulders better in quality than the Heritage, but if you are not going to shoot thousands of rounds through it, it will be a good buy.
If you are looking for a .22 for the wife, I'd suggest you let her have a major part of the decision. In the $200-$300 price range you can get an S&W 22A, Heritage, maybe a single six, Ruger MKIII, Buck Mark , Neos and P22. You have a wide choice and she may like one better than the other. I've never fired a Neos and don't like their looks, but I hear they are pretty good pistols. I've fired a Rough Rider and have a MKIII 22/45, 22A, single six, MKIII Hunter, MKIII GC, Buck Mark Standard and P22. She prefers shooting the 22a and single six. Her choice. Actually, she prefers my 80-year-old S&W .38 special because it "fits good."
If my wife wanted one of her own, I'd be happy to drive her to gun stores (if asked), but I'd stay out of any decision unless my opinion were requested.