I started with a 270, I still use the 270. Changing your ammo will effect your point of impact (POI) usually within 3 inches. Remember though at 100 yds 3 inches doesn't seem like that much of a difference, but at 2,3,400 yds it is moving farther and farther off your original sight in point. Making a complete miss very likely. Unfortunately, in California I am forced to use full copper bullets (which arne't cheap). So I use Barnes Triple X Shock and reload. Never have needed more than one shot, I can tell you that. Honestly for deer though, It's more than you need. You can seriously go buy a $20 box of Winchester SP's 130 grain and down em all day long. Deer are thin skinned and if you make even a decent shot it's a done deal.
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