When it comes to big hogs, the bigger the better. Anything under 200 lbs, a 357 in the boiler room is fine. Above that and I’d be taking a neck or brain shot. Big hogs don’t bleed well. And they can cover a lot of ground very quickly. You want to stop them as soon as possible. A friend of mine shot a big hog (almost 400lbs) a couple weeks ago with a 300 WinMag with 220 gr partitions at just over 130 yards. He took it like a champ and ran almost 200 yards. Very little blood trail. But the pig was full of it.
Hogs aren’t bullet proof. But the big ones are tough. If I’m chasing pigs, I leave my 44 Mag at home and take my 444 or 45/70. You never know when Mr. Big will step out. If he does and doesn’t offer the neck or brain, I want the biggest caliber I can. Because tracking pigs where I hunt can be pretty hair raising. YMMV