When I want a milder carry load in any .357 revolver, the 145-grain STHP is a good one, with a track record against real bad guys. In my hands, which are of course not necessarily like anyone else's hands, I need the milder stuff more in my 4" Speed Six than in my SP101 snubbies, as the latter kick straight back into my palm, with little muzzle rise, compared to the upward kick of the Speed Six, into the web of the hand.
The STHP also has more of a dull orange flame at the muzzle, compared to the whiter flash of some other .357 loads. Winchester does a good job of suppressing flash in their Silvertip revolver ammo; the same was true of the .41 mag Silvertips I used in my M58 back in the day.
Just to be clear, the 145-grain STHP is NOT a truly mild load, like the 125-grain Golden Sabers, the "short barrel" Gold Dots, or most of the 110-grain loads. It is still a serious stomp-'em load, just not loaded to the firewall like most of the 125-grain stuff, like the "Classic" Federal loads.