The thing about W296/H110 (same powder) is that it wants to be almost on the ragged edge to burn consistently, and then only with a magnum primer...
21gr under a 200gr bullet in .44 mag is not 'dangerous' per se (IMNSHO), but it may give you wide spsreads in velocity, and the potential for incomplete ignition and a stuck bullet...
A stuck bullet IS a dangerous situation...
Here is the warning that used to accompany H110:
Reduce H110 and Winchester 296 loads 3% and work up from there. H110 and Winchester 296 if reduced too much will cause inconsistent ignition. In some cases it will lodge a bullet in the barrel, causing a hazardous situation (Barrel Obstruction). This may cause severe personal injury or death to users or bystanders. DO NOT REDUCE H110 LOADS BY MORE THAN 3%.
That's what I'm going to do
If it were me (and it aint), I'd pull the bullets and start over...