Almost everybody is avoiding one of his questions. "Can I use Universal in my gun?" Yes...It compares to Unique. It's a midrange powder, but MAY be slightly cleaner.
I use a bit of Herco for this velocity-range, but almost any Alliant powder works. I ALWAYS keep some 2400 around for the hotter loads.
If you want to compare different bullets of the same weight, you want to compare "seating depth."
Of course, wwhen you change any componant, drop the powder charge, and work back up.
Have fun,
Gene