The thing is, I already own a 454 casull, so if I'm not getting higher velocities than that cartridge delivers (and most of the manuals don't) there's little reason to buy one. My particular interest in the 460 is in it's long range superiority to the 454 casull.
The reason loading manuals don't list velocities over 454 Casull velocities is because they don't consider their bullets adequate for 460 S&W Mag. velocities. The 460 S&W is capable of significantly higher velocities but you'll have to go outside of the published velocities of certain manuals (Speer for one).
The 460 S&W is rated for up to 65,000 psi per SAMI but if you don't size your cases enough you won't eject spent cases from your revolver easily at those pressure ranges though an Encore will eject them just fine. That's another reason the loads in manuals are as low as they are. Also, at the upper limits of pressure, brass life will not be what you'd expect out of a straight walled handgun cartridge (read head separations). You will also need a good crimp (better than a roll crimp) for high pressure loads or the bullets WILL walk (I don't crimp at all for my Encore).
As far as ranges the 460 is good for, I would consider it good for up to 225 to 250 yards tops because bullet drop after that is very significant. I've shot a 1.5 inch 3 shot group at 200 yards with my scoped Encore and have taken a Klipspringer (about the size of a large dog) at about 180 yards with it. Sighted in dead on at 100 yards, the drop from 100 to 200 yards is about 7.5 inches.
I also have a 460 S&W revolver with iron sights. My goal with that one is to be able to shoot 3 to 4 inch 3 shot groups at 100 yards with it with iron sights and I haven't gotten there yet. In fact, I would consider the 460 S&W a bit picky to load for and it took quite a bit of work to get my Encore shooting as well as it does.
By the way, I've shot even bullets meant for 45 Autos in both of my 460s with full house loads with no problems; your mileage may vary.