Your breakeven cost/time will depend entirely on both your cost of equipment and cost of components, both of which vary widely depending on your choices. 9-mm Luger costs me $2.26/box of 50, rifle about $3 to $4/box of 20 regardless of caliber, the difference in cost being mainly the choice of bullet.
Single stage presses are the least expensive and most flexible way to go...very inexpensive to change calibers, requiring only one shell holder (Say $3 to $5) and the dies, and perhaps a primer rod change (all you need is one large and one small). Presses don't wear out...used ones are as good as new ones, and are available if you search...check "used" shelfs at gun shops and the gun shows. Lee makes excellent dies at a very fair price...Midway is a good source. Aluminum frame presses are fine for pistol and .223, but for full-length resizing large rifle cases a cast iron frame press is advisable...less spring. Any progressive press is very expensive to change calibers...Say $20 to $40, less for a Lee, plus dies.
Cast bullets are fine for both rifle and pistol...I've done both, but find that current 500 lot prices for pistol are so low that it isn't worth my time. Cast, gas-checked bullets for rifle are rather scarce, however. I still occasionally cast a batch of 170-gr .30 bullets (Lyman U311291) for my .308 and .30-06 and my son's .30-30, and which, unsized, are excellent for .303 and 7.7 Jap.
Suggestions for low-cost reloading: (1.) Buy components in bulk, sharing costs with another reloader if possible (particularly useful for mail orders). (2.) Standardize on powder and buy in bulk rather than a bunch of very expensive little cans. (I use Win #231 for all pistol between 9-mm Makarov and .45 Colt, and #4895 for all rifle between .223 and .30-06.) (3.) Shop for bargains. There are a number of INET sellers of bulk surplus powders and bullets, and you may run across good deals at gun shows.
But, in any case, reloading adds to your fun of shooting. Shooting factory stuff is fun...but you get extra pride in shooting ammo you've made yourself.