anybody shoot laser grips left handed?

[rocinante]

I have a S&W 642 I wouldn't mind laser grips on but they look like my left handed thumb would be in the way or at least uncomfortable.

 

[WC145]

I have CT LG-105's on my S&W 360J and when practicing left handed my thumb does not get in the way nor does it compromise my grip.

 

[M2 Carbine]

I've got Crimson Trace Laser Grips on a couple S&W J Frames. No problem at all shooting left handed.