If it will help, the U22 Neos is the old Colt .22, which was the Colt Cadet (before Iver Johnson threatened suit), which was the old High Standard Duramatic.
But the older versions had a pushbutton safety while the Neos has an up-down safety. The takedown should be the same. Briefly, remove the magazine, retract and lock back the slide, unscrew the barrel screw and lift the barrel straight up. Then release the slide stop, letting the slide go forward off the frame. Careful with the firing pin and recoil springs.
HTH
Jim