cookejdr wrote <I've never seen an expanded handgun round. It rarely happens in human tissues....the most important factor in handgun wounding effectiveness is sufficient penetration to reach vital organs and/or break bones>
This is rather an astounding statement in view of the proliferation of hollowpoint and other expanding bullets on the market. What you write about penetration endorses FMJ bullets and by implication smaller caliber weapons as there is less need for speed without expansion. You sure you haven't been looking at entirely at mousegun wounds? Come to think of it, John Browning was indeed the designer of the very popular .380 APC 9X19mm Kurtz round, and Browning was known to get it right the first time around. And certainly British Intelligence, if there is such a thing, could not be wrong in recommending a .380 for James Bond. "Like a brick throught a window" is how they put it. That sounds like the kind of firepower more than adequate for self defense.
I spent years looking at autopsies as a part of my job. The most common calibers (in no particular order) were 9mm, .40, .45, and .357, although I have also seen 12 gauge, 30-30, .25acp , 22lr, .380 etc.
I was reading the famous/infamous FBI report from 1989 that led to the 10mm/.40 S&W development, when I realized I was never seeing expanded hp's in handgun fatalities. I asked one of our ME's (the dr's who perform the autopsies) and she said she rarely sees expanded hp handgun bullets. Keep in mind she sees gunshot wounds almost every day. I asked some of the other ME's, and they all gave the report: they rarely or never saw expanded handgun hp's. Sometimes you see jacket separation, but rarely expansion. Classic mushrooms? Never.
Anyway, I've posted about this before, sometimes to much derision. Whatever. This is what I saw over hundreds of cases, and I asked the ME's about their experiences from thousands of others, and it matched mine. YMMV.
-David