Well too, you might want to measure your Cylinder end-Chamber diameters, and Barrel Bore.
Older .45 Colt Revolver ran quite a bit larger Bullets than modern ones.
Checking yours will allow you to decide or elect appropriate Bullet diamaters.
BP Cartries are quite easy and fun to do one's self if you have a Loading Press or old Ideal Tong outfit and Dies right for the actual Diameter ( that's the hard part! All the dies I can find are too small for the old Diameter Revolvers).
Or use Hollow base Bullets...
Always compress the Black Powder Charge well...if you use filler on top, compress it all well regardless...usually one compreses in the act of seating the Bullet.
So work out where the Bullet base needs to be for a correct Crimp, and, fill the Case so the volume anticipates a good compression of the Powder ( and or filler also).