I'm dealing with a similar challenge in .223. I like to seat the bullet as close as possible to the rifling to reduce blow-by and hopefully have a more consistent start pressure. However, I have found that if the bullet actually touches the rifling, the velocity (and, presumably, pressure) rises markedly. So I tried to seat all of the bullets either into the rifling a few thousandths or off of the rifling a few thousandths, as suggested earlier on this thread. The idea was CONSISTENT START PRESSURE, and because the pressure change is so noticeable right at the point of contact, it seemed smart to seat the bullet either just on or just off the rifling. In practice, however, this was easier said than done. Especially when I was trying to seat the bullet just off the rifling. Any variations in neck tension would affect the overall length of the finished cartridge by at least a thousandth or two, and that was enough to markedly change velocity (pressure) when I was just a thousandth or two off the lands to begin with. So I tried seating INTO the lands a couple of thousandths instead, reasoning that the rifling would provide consistent start pressure. The problem seemed to be that resistance rose astronomically as the bullet went forward into the rifling, and therefore, overall length was even more critical than it was when was just off the rifling. This problem was no doubt compounded because my favorite bullets had a fairly sharp corner at the bottom of the ogive.
The only time I've gotten really consistent performance when I was seated into the rifling (and boy, did they perform!) was with some of those long, skinny berger bullets and that was when they were jammed into the rifling hard with a lot of neck tension. These days I'm concentrating on consistent neck tension and TOTAL CONROL OF OVERALL LENGTH, with a goal of getting as close to the rifling as possible without ever touching. For what it's worth I can tell you that this endeavor is made considerably easier by investing in premium prefinished, presorted cases. Good luck to you.