I know someone has already said it, but the SmartCarry is freakin awesome. I carry an officers model with slimline grips, a novak mag with a pretty big floorplate through attics, trees, under houses, etc and barely notice it 99% of the time. The only time it's a PITA is in a crawspace with rafters being horizontal to the direction of movement, cuz it hangs down some from the slack and catches on the rafters. That's no good, and it's not a design flaw, it's a size flaw.. I'm very skinny and the strap is a little bit too big to secure with the velcro and have a tight fit.
Also, in addition to not really noticing it in your pants, you have a hard time noticing it outside of your pants, too. I wear jeans all the time, but tried it out a lot with shorts, dress pants, etc. Shorts were fine, dress pants the overhang of the grip would really stand out by the pocket. An untucked shirt is an essential item for light clothing.
scrubs? should be just fine, especially if you have a pistol smaller than a 1911OM.
Additionally, with an ambidextrous safety it would normally be disengaged by the end of the day. I swapped out the ambi safety for a standard non extended safety and never had that problem again.
The pistol doesn't get sweaty at all, and i've had no problems in the rain either.
Buy it.
(may complicate trips to the bathroom)