As long as the home built firearm is not a destructive device, an any other weapon (such as a pistol with a vertical forward grip), short barrel rifle, short barrel shotgun or machinegun, does not fire from an open bolt and meets the requirements of 18 USC 922R for maximum number of imported parts on a "non sporting" semi-automatic rifle or shotgun, it should be good to go.
Disclaimer: I am not a lawyer.