Placement on anything is the name of the game. I shoot alot of wild hogs down this way, bought a .45/70, stoked up some 300gr XTP's to 2400fps and they generated 59lbs of recoil on my end. I took this super monster to the woods, drew down on an 80lb pig and let fly. I took out one shoulder, passed through the ribs on the offside and the critter ran off about 75yds. I've done the same with my .280, .308, and .270 many times and never had to deal with 59lbs of recoil.
You reach a point where to much power doesn't do much good on thin skinned critter four legged and two. Punch a hole with a 300gr .44 mag and a 230gr .45acp in someones lungs without tearing up any major central nervous system parts and do you think the bleed out rate would be any different?
I know a couple guys went and bought .338 win mags to hog hunt with, said you had to have the extra whump and range. But when the range gets out there, or the hogs are running, i'm rolling hogs with 150gr corelokts out of a .280 and they are trying to prep for the recoil.
I carry a .357 mag most of the time now, might go to a 9mm, found a p95 for $225 this week and snatched it up at a pawn shop. I carry a .22 from time to time, and have been known to have a Bianchi IWB stuffed with a Springfield 1911 from time to time. But the one thing is that whatever I am packing, I am shooting as much as I can afford or have time for. I'm really impressed with the Ruger right now, it's light and the dang thing shoots like a house afire. Was ringing 8"x8" plates at 50yds with Speer Lawman ammo the other day.
But confidence has to play a part in what we choose to use, I don't hunt hogs with a .22lr because I know that outside a few yards it is incapable of doing the job. I think some handgun calibers are marginal, truth be told all of them are, isn't a handgun made to get to the rifle? But we have to choose something, and if you can afford to shoot 5 boxes of 9mm ammo a week, instead of 2 boxes of .45acp, then i'd opt to the 9mm, because you will be proficient with it.
I really questioned the ability of some of the people I took the CHL class with, when they shot scores around the 170-180 mark out of 250, when I was shooting 248-250. What happens when you intro real stress to those folks? They needed to be out there with a gun they could afford to shoot, alot. I aint no pistolero but I do practice as much as I can and it shows, if I take a month or more off from it, I can see the results right on the paper.