I have an USP9f and two USP45f's. The one usp45 has over 9k rounds with only one failure caused by a ruptured case. The second has 2300 rounds through it no failures. The usp 9 has over 4k rounds with no failures. So, yeah, in my experience they are reliable. I love that I can either decock or carry condition 1. The grip texture feels excessive until you fire it then it glues your hand to the gun. The trigger is better, imho, than the glock, but no where near 1911 excellent. The paddle mag release is love it or hate it, but works fine for me, and really ejects spent mags. The finish is very tough.
Over all great pistols and would be my SHTF/ zombie apocalypse gun.