There are a lot of people (or so it seems) that will go hoggin with a 22 mag, shoot them in the ear.
As for me, I'd prefer a little more gun, I've had pigs with both shoulders blown out from a 30.06 at 30 yds still try to come after me.
If you were to use the .22mag and not get a DRT head shot, I wouldn't trail the pig, you might get a lovely ambush from a pissed of wounded pig.
As for the .380, I'd use something with a little more punch, maybe a .357 or larger for my pistol, preferably a 41mag or larger. Then again, I carry a 45 acp with me when I go, not to shoot them, more of a SHTF situation, and I carry it cause I own it and do not own a more powerful revolver.