Well, what do you really need?
Working/business/serious guns:
.38 snub
9mm service pistol or full-size .38/.357
CAR-15 (or .357 lever rifle, if both your pistols are .38/.357, this makes a lot of sense, even though it limits your rifle's range)
Hunting:
12 or 20 guage shotgun (birds)
.22 rifle/pistol -- close/small varmints, rabbits, squirrels
.50 cal muzzleloader or .308/.30'06 if you really have to have a centerfire rifle -- deer and bigger
CAR-15 -- coyotes, other bigger/farther varmints, can do for small deer in a pinch
Teaching others:
.22 pistol
.22 rifle
whatever student wants to move to from there
Just shooting:
.22 rifle/pistol
anything else on the "must-have" list as money allows for practice ammo, anything else on the "I really wants it" list, as money allows for less necessary guns.
Lots of crossover on this list. It's 7 guns, at its largest. If you go with the .357 lever rifle, and don't live somewhere long shots on big game are likely, then it does good double duty for deer, so down to 6. You can cut your long guns down to just a versatile shotgun (deer, birds, serious use) and a .22 if you must, for finances or whatever. I feel the need for a good, real rifle, but it's not a must-have for some. That's 5 guns. Cut your .22s down to one, because "who really needs more than one?" and you're at 4. Following that logic, you don't really "need" two pistols, do you? So just keep one, and you're at three: a .38 revolver, a shotgun, and a .22. And you'd probably get through your life just fine.
Be a little more boring, though. You can "logic" your way out of most of your possessions, really. You could probably get along with a used Civic or Sentra for most of your transportation needs, and maybe get a beat-up old Silverado or F150 for a couple grand (or less) for when you need a truck. If you live in a city, you probably don't "need" a truck, right? Probably don't "need" a closet full of clothes and shoes, either, right? Don't "need" a bunch of knives and pots in the kitchen, just 2 knives (paring knife and a 7 or 8 inch slicer/chef's), a cast iron frying pan, and a cast iron pot. Don't need 15 or 20 different pocket knives, just a little SAK Tinker or Recruit would probably cover everything you really use them for.
Simplification has attraction in a lot of ways. Folks get caught up in their "stuff" and the things they own often end up owning them, instead. Been thinking about that a lot lately, but ... I'm not selling much of anything, either. I've got one rifle I'd sell w/o heartburn, but most of the rest of the stuff in my safe is ... not for sale.
Nothing wrong with owning more stuff, if you want to. It's a hobby, and as long as you can afford what you're getting (not going on plastic), get what is most interesting to you. Then enjoy the heck out of it! Or just stick with logic, and buy only what you need/will really use. It's a personal decision.