S&W 4006. Only .40 I have any real experience with.
Same controls as my 5906 (which I like very much), all stainless steel, 10-shot mag (11 if you get pre-ban mags, but you are only losing one round if you use the 10-shots), nice trigger, full-size so it fits my hand well, more accurate than I am, points right for me. Probably a bunch of others I can't think of right offhand.
A lot of you guys voted for the Glock, and that's cool, they're good, but for me it's a S&W.
ANM