I have read for year that knockdown is a myth and I even understand their rationale. But I have seen a few examples that seemed to me, to be a knockdown. The last mule deer I shot vanished instantly. The moment I fired the shot I opened both eyes and distinctly remember the rifle rising in recoil and the deer was not there. AND... the deer was not dead. I walked up to the deer and it jumped up and ran. I have been knocked down, I have knocked down other people, and have seen other people knocked down. This is what it looked like to me. I shot a coyote with a 185 grain HP in a .45 ACP Officer's Model; same thing. I muffed the shot and hit it too far back; about in the center of the body. Again, I can remember shifting my focus from the front sight to the animal the moment the trigger broke and the coyote simply vanished from sight. I walked up and it wasn't dead; and no major bones were hit. Again, it appeared to me just like anything else I have ever seen that was knocked down by impact. In both cases the animal hit the ground in a fraction of a second after the shot.
But of course, if the bullet knocked it down, why doesn't this happen every time ?