I dunno...heard too many horror stories. One guy shot in the face with the P3AT in a dispute...spits the bullet out, goes back in his house, retrieves a revolver, comes back out and kills the guy who shot him. I read where a guy went to a hospital recently, drove himself there, and they found five .380 rounds in his chest...none were too deep. Oh sure, I've heard where a kid shot a Bear in the back with a .22 LR and it killed the bear...snapped the spinal cord. I'm not saying it cannot be done...but I say it is luck. A human being can have his heart explode and still have enough oxigenated blood in his system to close with and kill you. I don't believe the .380 is going to drop anybody in their tracks...even at close range, quite frankly.