If it is in need of cleanup, then start with a detail-strip-and-clean.
Sort out the gears and other parts in the shell plate carrier assembly and install new ones, and have some spares on hand. These are the parts most likely to have been abused and damaged, and may well have been the source of an un-technical owner's frustration.
Other parts to be routinely replaced would be the springs for case retention and the primer anvil spring. IOW, build your list of parts to order from Lee.
If the primer trough is at all nicked, grungy, or worn, get a new one--one for each size of primer, and get some extra trays. When you get these, lube them down with a slight amount of powdered graphite using a swab. Make sure the graphite is dry, not the spray-on stuff. You may need to bend the primer "shaker bar," or even replace the right rear post if its notches are well worn.
The case feeder does work reliably, but may need some tweaking for the Z-bar, and the Z-bar holder part mounted on the right front post may need to be replaced if it is well-worn.
When you set up the press, concentrate on setting the #1 die first, and then bring the PTED die into adjustment.
For the #3 / combined seater-crimper, you need to spend some time as both the die body and stem need to be adjusted to have a suitable crimp.
Tackle tweaking the case feeder slider last--hint: "The STP tip" in the Load-Master videos works well here, too.
Once the Pro 1000 is set up properly, it should work quite reliably for you. I added the the case feeder and collator setup, and when I was using it (and organized with extra filled primer trays, etc.), I could load 500 rounds of my typical semi-auto fodder per hour, using the Lee Auto Disk Measure.
The main disadvantages are the PITA routine for primer-caliber changes, and the 3-die paradigm. Because of the true progressive operation and the 3-die paradigm, it also is a lousy press to do load development work on--i.e., frequent charge weight changes, or bullet / crimp changes, etc.
Set up for one caliber for semi-auto ammo, it's a wonderful little press.
Jim H.