The 6th edition of Barnes' Cartridges of the World says that the M2 Ball round is a 152(-3) grain bullet clocking at 2740 +/- 30 ft/sec at 78 feet. Three possible powder charges are given: 50 grains of IMR4895, 50 grains of WC852, or 45 grains of CMR-100. Nominal case weight is 200(-20) grains.
Note that military powders are not necessarily an exact match in burning rate for commercial cannister powders having the same designation, and commercial and military cases may differ in their volume, which can affect the pressure generated by a given charge.