My P22 has fired 6,000+ rounds downrange. My wife really enjoys the pistol. I like it too, but it is a bit too small to hold comfortably. I have to significantly modify my grip. Even so, the pistol is very enjoyable.
Around 5,000 rounds I started having lots of problems with it. It was almost like the pistol just wore out. Lets of failures to eject including stove pipes and all out jams. I noticed the barrel housing was coming loose and tightened it, but it only fixed the problems for a few magazines. Finally, I gave up and sent the pistol to Smith and Wesson. Wow.
Smith and Wesson's customer service was ABSOLUTELY EXEMPLARY. I called them and they sent me a free shipping label. It took about 5 days for the shipping label to reach me by mail. I mailed the gun to S&W last Wednesday evening, and the pistol was returned to me today (Tuesday). It took them less than one week to fix the pistol including shipping both ways. They replaced the barrel and the extractor. It looks like they generally went through and tightened everything as well. I look forward to shooting it again.