+10000 about not teaching own wife,
I would offer to try to find an older smith and wesson or ruger DA revolver in DA. let her start with the SA and as she develops some hand strength and experience she can move up.
My daughter started shooting when she was 9, at first it was .22's but by the time she was 12 or so she was shooting 9mm and .38's at 14 she was handling .45 acp no problem and she manages .44 mags shortly after, it was all confidence, practice, and muscle tone.
No matter how small or tender you wife is, she can learn this stuff, and it really does not take long. a couple of times a week of some dedicated exercises or range time will have her managing a gun very quickly. I have seen women who could not hold the gun out and steady at all, within 3 weeks be able to rack the slide and hit the target.
PS, if she complains about sore hands after a range session, have her take two tylenol or advil before going out to shoot, really really reduces the soreness after the fact.