Gamestalker summed it up pretty well, but I will add this. There are a number of items which directly relate to the pressure in the chamber when you fire a round. Heavy bullets typically also have more friction along with the mass which creates more pressure behind the bullet. Primers are their own little ignition and create different pressures based upon type, brand, etc. Case capacity is another big consideration. You only mentioned 30-06, so you have a large case, but even so seating a bullet deeper into the case will cause pressure spikes due to the smaller case capacity. Seating too far out has its issues as well in that you can seat far enough out that your into the portion of the barrel which has friction which will try to keep the bullet inside the case longer, again having pressure spikes. Last but certainly not least is the amount of powder going into the case. There are multiple ways to measure but the most commonly accepted means is by weight. Volume is used a lot as well, but is not nearly as precise as weight measurements because a .5cc loose load may be X grains, and a slightly compressed load may be x+5 grains. I don't intend to scare you by mentioning all the ways that you can blow yourself up, but to emphasize the care that you must take to load safe ammunition.
With that said, you have got good bullets that are known for being decent performers both on paper and on game. I suggest looking at your reloading data, loading 5 each in increments from starting load up to max load in some measurement that makes sense...I typically divide the difference by 5 and use that as my ladder rungs from bottom to top. Make sure you know what is what...a sharpie works well. Expect the lighter loads to perform poorly, and the loads to improve to a point then suddenly fall apart. Look for your tightest group, and then set that as your midpoint and do another workup from the load before it, to the load after it. You will quickly find a very very accurate load custom tailored to your specific gun. When I get back to my books I will take a photo of data and post it for you to use as a reference.