I would second a full size pistol. .22 is not necessary - I'd go for 9mm. It's a good sized load and relatively cheap to shoot. Also versatile for self defense, competition, and target practice. Revolvers are great guns to learn on, but either an auto or revolver are good - just be safe and get some handgun training if possible for helping you understand about proper safe handling. Good luck in whatever you choose, and be careful, buying handguns can be an addiction. ;-)