I have a friend that started reloading 6 or 7 years ago. One day he called and said his Blackhawk was locked up after pulling the trigger. I knew he’d been shooting his reloads and asked if the recoil or bang seemed any different and he said no.
After he tried to disassemble his gun and finally had to take it to a gunsmith in a bag, it was discovered that a bullet was stuck between the cylinder and forcing cone. Presumably he didn’t put a powder charge in that one...
A week or so after his gun was put back together we were at the range and he offered me a cylinder of his reloads to shoot in my own gun. When he wasn’t looking I put them in my ammo can and continued to shoot my own factory ammo. Those 6 rounds are still sitting in a baggy in my ammo can.
I keep them handy in case I ever run completely out of ammo, that way I can take them to the range and throw them at the target. Because I sure as heck ain’t loading them in my gun!