JJE
Member
For me, it depends on the range to target. I'd prefer to keep both eyes open, since closing one eye creates a little bit of physical stress. But I can only do it at short ranges - out to 25 feet or so - so that's how I practice with snubby handguns and compact autos. If I'm shooting a full-size handgun at 50 feet or farther, both eyes open just doesn't work for me - I get confusing double images, so I have to close one eye.